Allogeneic Hematopoietic Stem Cell Transplantation for Congenital Immune Dysregulatory Disorders
Primary immunodeficiency disorders that predominantly affect immune regulation and mechanisms of self-tolerance have come into the limelight, because at least for a subgroup of monogenetic disorders, a targeted therapy has become available.Nevertheless, their management often involves the treatment of severely compromising, refractory, multi-organ